Dr. Meysam Sarshar is an Associate Professor of Clinical Microbiology at Link Campus University of Rome and a Principal Investigator at Bambino Gesù Children’s Hospital (IRCCS), Italy. He also serves as Chairperson and International Relations Manager at ecoZist Corp. since 2023. With a Ph.D. in Infectious Diseases, Microbiology, and Public Health from Sapienza University of Rome, his research spans microRNAs in host–pathogen communication, biomarkers for pediatric diseases, nanotechnology, and organoid-based models.

He has held postdoctoral and visiting scientist positions in Italy and Iran, contributing significantly to projects on uropathogenic E. coli, gut microbiota, and infectious disease mechanisms. Dr. Sarshar has authored dozens of peer-reviewed publications, book chapters, and patents, and he actively serves on editorial and reviewer boards of international journals.

Recipient of multiple research grants and scientific awards, he has extensive experience in molecular biology, microbiology, cell culture, and bioinformatics. His international collaborations focus on advancing antimicrobial resistance studies, organoid technology, and translational microbiology for human health.

PERSONAL INFORMATION

Meysam Sarshar

m.sarsharjeryandeh@unilink.it

meysam.sarsharjeryandeh@opbg.net

https://scholar.google.it/citations?user=oQaNVqMAAAAJ&hl=en&oi=ao   

https://www.scopus.com/authid/detail.uri?authorId=55207523600 

https://orcid.org/0000-0002- 5726-2090

EDUCATION AND QUALIFICATION

20/12/2023-Present          Associate Professor in Clinical Microbiology (06/A3 SSD MED/07)

Link Campus University of Rome (Italy)

01/03/2020–Present         Principal Investigator

Research Laboratories, Bambino Gesù Children’s Hospital, IRCCS, Rome (Italy)

Research Activities:

“microRNAs as messenger molecules for bacteria-host communications”

“Circulating biomarkers for the diagnosis and follow up of pediatric diseases and use of nanotechnology and 3D bioprinting approaches in biomedicine”

“Fecal microRNAs potential biomarkers of celiac disease and study of phenotypic and genotypic characteristics of E. coli for disease classification”

Association of intestinal permeability-derived miRNAs and pathogenic E. coli with insulin resistance “Feeding” cohort.

28/05/2021                        Italian National Scientific Qualification (ASN 2018/2020) for Associate Professor (Scientific field: Microbiology and Clinical Microbiology, 06/A3 SSD MED/07)

01/03/2018–01/03/2020 Postdoctoral Research Fellow

Department of Public Health and Infectious Diseases, Sapienza University of Rome (Italy)

Research Activities:

“Scientific assessment of mechanical and physical effects of D-mannose for the prevention of urinary tract infections (UTIs)”

“FimH and anti-adhesive therapeutics: mannopyranoside antagonists as potential adhesion inhibitors against uropathogenic Escherichia coli (UPEC)

“Adaptation strategies of UPEC: evaluation of transcriptional profiles of virulence/fitness factors of strain CFT073 incubated in synthetic urine and in contact with bladder cells”

01/12/2017–30/11/2018 Visiting Scientist

Microbiology Research Center (MRC), Pasteur Institute of Iran, Tehran (Iran)

Project title:

“Evaluation of gut microbiota pattern and related metabolites in Type 1 & 2 diabetic patients”

01/10/2014–13/02/2018 Ph.D. in Infectious Diseases, Microbiology and Public Health                            EQF level 8

Department of Public Health and Infectious Diseases, Microbiology Section, Sapienza University of Rome (Italy)

Thesis title:

“Escherichia coli colonizes colorectal adenomatous polyps: insights into  genotypic, phenotypic and pro-carcinogenesis features”

01/03/2017–31/08/2017  Doctoral Fellowship

FILAS S.p.A. Foundation Group, Lazio (Italy)

Department of Public Health and Infectious Diseases, Microbiology Section, Sapienza University of Rome, Rome (Italy)

Project title:

“Quantification and validation of innovative procedures for titration of DNA and RNA viruses”

15/06/2008–20/09/2012    M.Sc. thesis/Project assistant                                                                                  EQF level 7

Department of Microbiology, Molecular Biology Unit, Institute Pasteur of Iran, Tehran (Iran)
Thesis title:

“Application of oligonucleotide array method for the rapid detection of foodborne pathogens”

20/09/2007–20/09/2010

M.Sc. in Cellular and Molecular Biology- Microbiology

Department of Biology, Islamic Azad University of Jahrom, Jahrom (Iran)

EQF level 7

01/06/2003–

06/09/2007

B.Sc. in Cellular and Molecular Biology- Microbiology

Department of Biology, Islamic Azad University of Tonekabon, Tonekabon (Iran)

EQF level 6

PERSONAL SCIENTIFIC COLLABORATIONS

2018–Present “Developing of bacteria-organoids co-cultivation experimental models and assessing the beneficial E. coli-based probiotics in IBD patient-derived intestinal organoids” (Sapienza University of Rome, Italy)

2019–Present “Intestinal organoids as a new model to unravel the role of exosomes in host- nematode interaction” (Sapienza University of Rome, Italy)

2019–Present “Therapeutic effects of FimH mannopyranoside antagonists as potential adhesion inhibitors against Uropathogenic E. coli (UPEC)” (Sapienza University of Rome, Italy and Department of Chemistry, Université du Québec à Montréal, Canada)

2020–Present “Taking it personally: identification of human-derived commensal E. coli as beneficial probiotics targeted for IBD” (Sapienza University of Rome, Italy)

2021–Present “Evaluation of the impact of bacterial superinfections in post-COVID19 patients and surveillance on antimicrobial resistance of major pulmonary pathogens” (Department of Human Sciences and Promotion of the Quality of Life, San Raffaele Roma Open University, Italy) 2021-Present “Network analysis of circulating and fecal microRNAs associated with intestinal E. coli pathoadaptation as predictors of obesity and co-existing comorbidities”  (Research Laboratories, Bambino Gesù Children’s Hospital, Rome, Italy)

JOB-RELATED SKILLS

Molecular biology techniques: Extraction of DNA, RNA, lipopolysaccharides and proteins from bacteria and eukaryotic cells, agarose and polyacrylamide gel electrophoresis, cloning, PCR, RT- PCR, Real-Time PCR, DNA sequencing, protein expression in bacterial hosts, Drug susceptibility testing (MIC), Dot blot hybridization, bacterial genotyping and phylogenetic techniques: RAPD-PCR, MLST and ERIC-PCR.

Microbiological techniques: Sterilization methods, preparation of culture media, cultivation of pathogenic and not pathogenic bacteria, isolation and preparation of pure cultures, preservation of microorganisms, Gram staining technique, bacteria identification using biochemical and molecular biologytechnique; bacterialconjugation, transductionand transformation, preparation and analysis of bacterial biofilms, motility assays, genotoxins production assays.

Cell cultures: Maintenance and propagation of cell cultures, techniques for cell separation, cell storage (freezing and thawing), bacterial infection, transfection. Ex vivo samples treatment (biopsies, fecal samples, swabs, etc.) for bacterial recovery and identification.

Statistical: Word processor, Excel, Vector NTI advance11, Gene Runner, GraphPad Prism, SPSS.

Images analysis tools: Photoshop CS6, ImageJ, Adobes, Image View software

Bioinformatics software: BLAST, CLUSTAL

Databases: NCBI, UNIPROT

SCIENTIFIC PUBLICATIONS

  1. Mousavifar L, Sarshar M, et Insightful Improvement in the Design of Potent Uropathogenic E. coli FimH Antagonists. Pharmaceutics, 2023, 15(2), 527; https://doi.org/10.3390/pharmaceutics15020527.
  2. Perruzzaa L, Zagaglia C, Vitiellod L, Sarshar M, et The Shigella flexneri virulence factor apyrase is released inside eukaryotic cells to hijack host cell fate. Microbiology Spectrum, 2023, 11(6), e00775-23; https://doi.org/10.1128/spectrum.00775-23.
  3. Mukherjee S, Patra R, Behzadi P, Masotti A, Paolini A, Sarshar M. Toll-like receptor- guided therapeutic intervention of human cancers: molecular and immunological Front.                     Immunol,                      2023, 14:1244345; https://doi.org/10.3389/fimmu.2023.1244345.
  4. Behzadi P, García-Perdomo HA, Autrán Gómez AM, Pinheiro M, Sarshar Uropathogens, urinary tract infections, the host-pathogen interactions and treatment. Front. Microbiol, 2023, 14:1183236; doi: 10.3389/fmicb.2023.1183236
  5. Ghorbani-Dalini S, Azarpira N, Sangtarash MH, Urbach V, Yaghobi R, Soleimanpour- Lichaei HR, Sarshar M. Optimization of 3D islet-like cluster derived from human pluripotent stem cells: an efficient in vitro differentiation Gene. 2022; 84500:146855;  https://doi.org/10.1016/j.gene.2022.146855.
  6. Sarshar M, Scribano D, Palamara AT, Ambrosi C, Masotti The Acinetobacter baumannii model can explain the role of small non-coding RNAs as potential mediators of hostpathogen interactions. Front. Mol. Biosci, 2022; 9:1088783. https://doi.org/10.3389/fmolb.2022.1088783
  7. Bellini I, Scribano D, Sarshar M, et Inflammatory response in Caco-2 cells stimulated with Anisakis messengers of pathogenicity. Pathogens, 2022, 11(10), 1214; https://doi.org/10.3390/pathogens11101214.
  8. Behzadi P, Ambrosi C, Scribano D, Zanetti S, Sarshar, M, et Current perspectives on Pseudomonas aeruginosa: epidemiology, virulence and contemporary strategies to combat multidrug-resistant (MDR) pathogens. Front. Microbiol. 2022; 13, 975616. https://doi.org/10.3389/fmicb.2022.975616.
  9. Sarshar M, Scribano D, Behzadi P, Masotti A, Ambrosi Outer membrane vesicles are the  powerful  cell-to-cell  communication  vehicles  that  allow  bacteria  to  monitor extracellular milieu. ExRNA. 2022; https://dx.doi.org/10.21037/exrrna-22-18.
  1. Behzadi P, Sameer AS, Nissar S, Banday MZ, Gajdács M, García-Perdomo HA, Akhter K, Pinheiro MB, Magnusson P, Sarshar M, Ambrosi The Interleukin-1 (IL-1) Superfamily Cytokines and Single Nucleotide Polymorphisms. J Immunol. Res. 2022; 2054431.  https://doi.org/10.1155/2022/2054431.
  2. Paolini A, Baldassarre A, Bruno SP, Felli C, Muzi C, Ahmadi Badi S, Siadat SD, Sarshar M, Masotti Improving the diagnostic potential of extracellular miRNAs coupled to multiomics data by exploiting the power of Artificial Intelligence. Front Microbiol. 2022; 13: 888414. https://doi.org/10.3389%2Ffmicb.2022.888414.
  3. Paolini A, Sarshar M, et Biomarkers to Monitor the Adherence to Gluten-free Diet by Celiac Disease Patients: Gluten Immunogenic Peptides and Urinary miRNAs. Foods. 2022; 11(10), 1380; https://doi.org/10.3390/foods11101380.
  4. Marazzato M, Scribano D, Sarshar M, et Genetic Diversity of Antimicrobial Resistance and Key Virulence Features in Two Extensively Drug-Resistant Acinetobacter baumannii Isolates. Int J Environ Res Public Health. 2022; 19(5), 2870. https://doi.org/10.3390/ijerph19052870.
  5. Sarshar M, et Adaptive strategies of the uropathogenic Escherichia coli CFT073: From growth in lab media to virulence during host cell adhesion. Int. J. Microbiol. 2022; 25(3), 481–494.  https://doi.org/10.1007/s10123-022-00235-y.
  6. Pompilio A, Scribano D, Sarshar M, et Gram-negative bacteria holding together in a biofilm: The Acinetobacter baumannii way. Microorganisms. 2021; 9 (7), 1353. doi: 10.3390/microorganisms9071353.
  7. Scribano D, Sarshar M, et Urinary tract infections: Can we prevent uropathogenic Escherichia coli infection with dietary intervention. Int J Vitam Nutr Res. 2021; 1-5. doi:10.1024/0300-9831/a000704.
  8. Sarshar M, et Acinetobacter baumannii: An Ancient Commensal with Weapons of a Pathogen. Pathogens. 2021; 10(4):387. https://doi.org/10.3390/pathogens1004038.
  9. Ambrosi C, Prezioso C, Checconi P, Scribano D, Sarshar M, et SARS-CoV-2: Comparative analysis of different RNA extraction methods.  J Virol Methods. 2021; 287:114008. doi: 10.1016/j.jviromet.2020.114008.
  10. Ambrosi C, Scribano D, Sarshar M, et Acinetobacter baumannii Targets Human Carcinoembryonic Antigen-Related Cell Adhesion Molecules (CEACAMs) for Invasion of Pneumocytes. mSystems. 2020;5(6):e00604-20. doi: 10.1128/mSystems.00604-20.
  11. Sarshar M, et Fecal microRNAs as Innovative Biomarkers of Intestinal Diseases and Effective Players in Host- Microbiome Interactions. Cancers (Basel). 2020; 12(8):2174. doi: 10.3390/cancers12082174.
  12. Hozhabri H, Piceci Sparascio F, Sohrabi H, Mousavifar L, Roy R, Scribano D, De Luca A, Ambrosi C, Sarshar M. The Global Emergency of Novel Coronavirus (SARS-CoV-2): An Update of the Current Status and Int J Environ Res Public Health. 2020; 17(16):5648. doi: 10.3390/ijerph17165648.
  13. Scribano D, Sarshar M, et d-Mannose Treatment neither Affects Uropathogenic Escherichia coli Properties nor Induces Stable FimH Modifications. Molecules. 2020; 25(2):316. doi: 10.3390/molecules25020316.
  14. Sarshar M, et FimH and Anti-Adhesive Therapeutics: A Disarming Strategy Against Uropathogens. Antibiotics (Basel). 2020; 9(7):397. doi: 10.3390/antibiotics9070397.
  15. Mardani Valandani F, Ghorbani-Dalini S, Ramzi M, Aghababa H, Sarshar M, et Protective Effect of HLA-E∗0101∕∗0103 Genotype in Survival of Patients After Allogeneic Hematopoietic   Stem   Cell   Transplant.   Exp   Clin   Transplant.   2020   Apr   7.   doi: 10.6002/ect.2019.0370.
  1. Ghorbani-Dalini S, Azarpira N, Sangtarash MH, Soleimanpour-Lichaei HR, Yaghobi R, Lorzadeh S, Sabet A, Sarshar M, Al-Abdullah Optimization of activin-A: a breakthrough in differentiation of human induced pluripotent stem cell into definitive endoderm. 3 Biotech. 2020; 10(5):215. doi: 10.1007/s13205-020-02215-3.
  1. Ambrosi C, Sarshar M, et Colonic adenoma- associated Escherichia coli express specific           phenotypes.            Microbes           Infect.           2019;                       21(7):305-312.         doi: 10.1016/j.micinf.2019.02.001.
  1. Sarshar M, et A simple, fast and reliable scan-based technique as a novel approach to quantify intracellular bacteria. BMC Microbiol. 2019; 19(1):252. doi: 10.1186/s12866- 019-1625-1.
  2. Scribano D, Marzano V, Levi Mortera S, Sarshar M, et Insights into the Periplasmic Proteins of Acinetobacter baumannii AB5075 and the Impact of Imipenem Exposure: A Proteomic Approach. Int J Mol Sci. 2019; 20(14):3451. doi: 10.3390/ijms20143451.
  3. Ahmadi Badi S, Moshiri A, Fateh A, Rahimi Jamnani F, Sarshar M, et Microbiota- Derived Extracellular Vesicles as New Systemic Regulators. Front Microbiol. 2017; 8:1610. doi: 10.3389/fmicb.2017.01610.
  4. Sarshar M, et Genetic diversity, phylogroup distribution and virulence gene profile of pks positive Escherichia coli colonizing human intestinal polyps. Microb Pathog. 2017; 112:274-278. doi: 10.1016/j.micpath.2017.10.009.
  5. Nasrabadi Z, Ranjbar R, Poorali F, Sarshar M. Detection of eight foodborne bacterial pathogens by oligonucleotide array Electron Physician. 2017; 9(5):4405- 4411. doi: 10.19082/4405.
  6. Ranjbar R, Mortazavi SM, Mehrabi Tavana A, Sarshar M, et Simultaneous Molecular Detection of Salmonella enterica Serovars Typhi, Enteritidis, Infantis, and Typhimurium. Iran J Public Health. 2017; 46(1):103-111.
  7. Ghorbani-Dalini S, Kargar M, Doosti A, Abbasi P, Sarshar M. Molecular Epidemiology of ESBL Genes and Multi-Drug Resistance in Diarrheagenic Escherichia Coli Strains Isolated from Adults in Iran J Pharm Res. 2015; 14(4):1257-62.
  8. Souod N, Sarshar M, et The study of the oipA and dupA genes in Helicobacter pylori strains and their relationship with different gastroduodenal diseases. Gastroenterol Hepatol Bed Bench. 2015; 8(Suppl 1): S47-53.
  9. Sarshar M, et Simultaneous Detection of Escherichia coli, Salmonella enterica, Listeria monocytegenes and Bacillus cereus by Oligonucleotide Microarray. Int J Enteric Pathog. 2015; 3(4): e30187.
  10. Momtaz H, Karimian A, Madani M, Safarpoor Dehkordi F, Ranjbar R, Sarshar M. Uropathogenic Escherichia coli in Iran: serogroup distributions, virulence factors and antimicrobial resistance Ann Clin Microbiol Antimicrob. 2013; 12:8. doi: 10.1186/1476-0711-12-8.
  11. Souod N, Kargar M, Doosti A, Ranjbar R, Sarshar M. Genetic Analysis of cagA and vacA Genes in Helicobacter Pylori Isolates and Their Relationship with Gastroduodenal Diseases in the West of Iran Red Crescent Med J. 2013; 15(5):371-5. doi: 10.5812/ircmj.3732. Epub 2013 May 5.
  12. Momtaz H, Dehkordi FS, Hosseini MJ, Sarshar M. Serogroups, virulence genes and antibiotic resistance in Shiga toxin-producing Escherichia coli isolated from diarrheic and non-diarrheic pediatric patients in Gut Pathog. 2013; 5(1):39. doi: 10.1186/1757-4749- 5-39.
  13. Momtaz H, Souod N, Dabiri H, Sarshar M. Study of Helicobacter pylori genotype status in saliva, dental plaques, stool and gastric biopsy World J Gastroenterol. 2012; 18(17):2105-11. doi: 10.3748/wjg. v18.i17.2105.
  14. Ranjbar R, Mohseni A, Moosavi A, Sarshar M, et The Prevalence of Sodc1 and Sope1 genes among the clinical serotypes of Salmonella enterica in Tehran, Iran. J. Mil. Med. 2014; 16(3).
  15. Ranjbar R, Sarshar M. The study of genetic diversity among clinical strains of Salmonella enterica serovar typhimurium. J. Mil Med. 2012; 14(1): 43-47.
  1. Sarshar M, et Detection of Escherichia coli, Salmonella enterica and Shigella dysenteriae by analysis of 23S ribosomal DNA gene. J. Isfahan. Med Sch. 2013: 30(219); 2333-43. [In Persian]
  2. Ahmadi Z, Ranjbar R, Sarshar M. Genotyping of Salmonella enterica Serovar enteritidis strains isolated from clinical samples by Pulsed-Field Gel Electrophoresis (PFGE). J. Isfahan. Med Sch. 2013; 31(240): 819-29. [In Persian]
  1. Sarshar M, et The study of antibiotic resistance and distribution of tetracycline resistance genes of diarrhogenic E. coli from pediatric patients. Iranian journal of infectious diseases and tropical medicine. 2012; 17(57): 13-18. [In Persian]
  2. Ghorbani-Dalini S, Kargar M, Doosti A, Abbasi P, Sarshar M. Survey of Multidrug- resistant (MDR) ESBLs producing diarrheogenic coli strains isolated from children under 5 Years of Age. Iranian journal of infectious diseases and tropical medicine. 2012; 17(56): 13-19. [In Persian]

BOOK CHAPTER

  • Karami A, Sarshar M, et Book tittle: The Prokaryotes: Other Major Lineages of Bacteria and The Archaea. Chapter: The Phylum Spirochaetaceae. Springer Berlin Heidelberg. Volume, 97836423895422014, 2014, pp: 915-929.
  • Gajdác M, García-Perdomo HA, Sarshar M, et Book title: The Immune and Non- Immune Systems Related Cytokines. Chapter: A World of Wonders: Interleukin-1 (IL-1) and IL-2 Families. IntecOpen, 2021, doi: 10.5772/intechopen.98664.

CONFERENCES

  1. Perruzza L, Sarshar M, et The Shigella flexneri virulence factor apyrase is released inside eukaryotic cells to manipulate host cell fate. 50th Italian National Congress of Microbiology. 2022, Napoli, Italy.
  2. Sarshar M, et Fecal-associated Enterobacterales isolates from celiac disease patients: could dietary sugars drive changes in bacterial composition? 50th Italian National Congress of Microbiology. 2022, Napoli, Italy.
  3. Scribano D, Sarshar M, et The protein HslJ boosts Acinetobacter baumannii survival against oxidative stress. 50th Italian National Congress of Microbiology. 2022, Napoli, Italy.
  4. Sarshar M, et Adaptive strategies of uropathogenic Escherichia coli CFT073: From growth in lab media to virulence during host cell adhesion. 49th Virtual Italian National Congress of Microbiology. 2021, Milan, Italy.
  5. Ambrosi C, Sarshar M, et Intestinal organoid modeling for intestinal bacteria competition assay. 49th Virtual Italian National Congress of Microbiology. 2021, Milan, Italy.
  6. Scribano D, Sarshar M, et D-mannose treatment neither affects uropathogenic Escherichia coli properties nor induces stable FimH modifications. 49th Virtual Italian National Congress of Microbiology. 2020, Milan, Italy.
  7. Scribano D, Sarshar M, et Fatal attraction: Acinetobacter baumannii exploits carinoembryonic antigen-related cell adhesion molecules (CEACAMs) for cellular adherence. 12th International symposium on the Biology of Acinetobacter. 2019, Frankfurt, Germany.
  8. Scribano D, Sarshar M, et Fatal attraction: Acinetobacter baumannii exploits carcinoembryonic antigen‐ related cell adhesion molecules (CEACAMs) for cellular adherence. 47th Italian National Congress of Microbiology. 2019, Rome, Italy.
  9. Scribano D, Marzano V, Levi Mortera S, Sarshar M, et Insights into the periplasmic proteins of Acinetobacter baumannii AB5075 and the impact of imipenem exposure: a proteomic approach. 47th Italian National Congress of Microbiology. 2019, Rome, Italy.
  10. Ambrosi C, Perruzza L, Rottoli E, Strati F, Sarshar M, et Apyrase, the Shigella flexneri virulence factor downregulates caspases activity through the degradation of intracellular ATP. 46th Italian National Congress of Microbiology. 2018, Palermo, Italy.
  11. Sarshar M, et Genetic diversity, phylogroup distribution and virulence gene profile of pks+ Escherichia coli colonizing human intestinal polyps. 8th BeMM Symposium, Biology and Molecular Medicine. Sapienza University of Rome. 20 November 2017, Rome, Italy
  12. Sarshar M, et A new, fast and reliable technique for quantification of intracellular bacteria by In- Cell Western Odyssey Assay. 45th Italian National Congress of Microbiology. 2017, Genova, Italy.
  1. Sarshar M, et Escherichia coli colonizes colorectal adenomatous polyps: insights into genotypic and phenotypic features. 45th Italian National Congress of Microbiology. 2017, Genova. Italy.
  2. Sarshar M, et Genotoxic Mucosa-Associated Escherichia coli in colon diseases: bad bugs in our gut. 44th Italian National Congress of Microbiology. 2016, Pisa, Italy.
  3. Sarshar M, et The study of tetracycline resistance and ESBLs in diarrheagenic E. coli strains isolated from southwest of Iran. 4th EKMUD Congress (Infectious Diseases & Clinical Microbiology). 2012, Istanbul, Turkey.
  4. Ghorbani-Dalini S, Kargar M, Doosti A, Sarshar M, et Prevalence of s, m and i allels of vacA gene in Helicobacter pylori strains and gastric disorders in Iranian population. 4th EKMUD Congress (Infectious Diseases & Clinical Microbiology). 2012, Istanbul, Turkey.
  5. Noorbazargan H, Momtaz H, Sarshar M, et A study of antibiotic resistance genes of diarrheagenic Escherichia coli from young children in Tehran, Iran. 4th EKMUD Congress (Infectious Diseases& Clinical Microbiology). 2012, Istanbul, Turkey.
  6. Sarshar M, et Use of 23S rDNA gene diversity for the discrimination of foodborne pathogenic bacteria by oligonucleotide microarrays. 4th Ditan International Conference on Infectious Diseases. 2010, Beijing, China.
  7. Kargar M, Ghorbani-Dalini S, Doosti A, Abbasi P, Sarshar M. Multiplex PCR assay for rapiddetermination of blaTEM, blaSHV and blaCTX-M genes in diarrheagenic coli isolated from Iran, Shiraz. 5th Ditan International Conference on Infectious Diseases. 2011, Beijing, China.
  8. Ghorbani-Dalini S, Kargar M, Doosti A, Sarshar M, et Quantitation of bacteria in gastric biopsy specimen from patients with gastrointestinal disorders: relationship between counts and clinicalfeatures. 5th Ditan International Conference on Infectious Diseases. 2011, Beijing, China.
  9. Sarshar M, et Clarithromycin resistance assessment in Helicobacter pylori isolates using 23S rRNA gene molecular markers. 5th Ditan International Conference on Infectious Diseases. 2011, Beijing, China.

RESEARCH SUPPORT

01/03/2015–Present

  • Research collaborator in a research project entitled: Role of Colibactin-producing Escherichia coli strains in the onset of polyp and colorectal cancer supervised by Annamaria Pronio. Sapienza University of Rome, Italy. protocol number: C26A15EY8F.
  • Participation in a research project entitled: Apyrase, the Shigella flexneri virulence factor downregulates caspases activity through the degradation of intracellular ATP supervised by Fabio Grass. Institute for Research in Biomedicine, Bellinzona, Switzerland.
  • Research collaborator of the project “Evaluation of gut microbiota pattern and related metabolites in Type 1 & 2 diabetic patients and Microbiota-derived extracellular vesicles as new Systemic regulators in health and ” coordinated by Prof. Seyyed Davar Siadat at the Microbiology Research Center (MRC), Pasteur Institute of Iran.
  • Participation in the research activity within the project “optimization of activin A, a breakthrough in differentiation of human induced pluripotent stem cell (iPSC) into definitive endoderm (DE) and evaluation of different human leukocyte antigen (HLA) genotypes in survival of patients after allogeneic hematopoietic stem cell transplant” coordinated by Negar Azarpira, Transplant Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
  • Research collaborator of project “Proteomic approach to identify periplasmic protein(s) associated with carbapenem resistance in the Acinetobacter baumannii model strain AB5075″ supervised by Carlo Zagaglia. protocol number: RP11715C7DA6918A, Sapienza University of Rome, Rome, Italy.
  • Participation in the research activity within the project “Circulating miRNAs and fecal miRNAs as  diagnostic  and/or  prognostic  biomarkers  of  pediatric  disease;  use  of nanotechnology approaches and 3D bioprinting for the characterization and delivery of non-coding RNAs from animal, bacteria and vegetable origin.” Coordinated by Prof. Andrea Masotti, Research Laboratories, Bambino Gesù Children’s Hospital, IRCCS, Rome, Italy.
  • Participation in the research activity within the project “Shedding light on the pathogenic role of colibactin-producing Escherichia coli in precancerous colorectal lesions: an Italian/Iranian ” coordinated by Prof. Anna Teresa Palamara (Sapienza University of Rome, Italy) and Prof. Saeid Bouzari (Scientific Director of the Pasteur Institute of Tehran, Iran).
  • Participation as a collaborator in the research activities within the project “Development of standardized analytical protocols for the contamination control of medical devices caused Burkholderia cepacia ” coordinated by Prof. Anna Teresa Palamara, Sapienza University of Rome, Rome, Italy.
  • Collaboration with Giovanni Di Bonaventura, Department of Medical, Oral and Biotechnological Sciences at the “G. d’Annunzio” of Chieti-Pescara, within the research project “genotypic and phenotypic characteristics and in vivo pathogenicity of adenoma-associated E. coli isolates in patients presenting adenomatous colonic polyps”.
  • Collaboration with Bernhard B. Singer, Institute of Anatomy, Medical Faculty, University Duisburg-Essen, Essen, Germany, within the research project entitled “Acinetobacter baumannii targets human carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) for invasion of pneumocytes.”
  • Participation in the research activity within the industrial research and experimental development project in the 12 Specialization Areas identified by the NAOCON PNR 2015- 2020 Research Project (ARS01_00597) “New antimicrobials obtained from compounds of natural origin”, in collaboration with the Anna Teresa Palamara, Sapienza University of Rome, Rome, Italy
  • Participation as a component in the research activities of the project entitled: “Analysis of Biofilm and Antibiotic Resistance in Neuroinjured patients” in the National Military Research Plan (PNRM) called ABRAN, supervised by Anna Teresa Palamara, Sapienza University of Rome, Rome, Italy
  • Participation as a component in the research activities of the project entitled: “Resistome Genomic Analysis of Nosocomial Infections of Operational Theaters” in the National Military Research Plan (PNRM) called AGRINTO, supervised by Anna Teresa Palamara, Sapienza University of Rome, Rome, Italy
  • Collaboration with the research group supervised by René Roy, Department of Chemistry, Université du Québec à Montréal, Centre-Ville, Montréal, Canada, within a common project of research entitled “Therapeutic effects of FimH Mannopyranoside antagonists as potential adhesion inhibitors against Uropathogenic Escherichia coli (UPEC).
  • Participation as a component in the research activities of the project entitled: “Water Genomic Analysis of Operative Theaters” within the program of “Interforce Health Research”, National Plan of Military Research (PNRM) called AGITO, supervised by Anna Teresa Palamara, Sapienza University of Rome, Rome, Italy
  • Participation in the research activity within the research projects “Deciphering host-parasite interactions using an in vitro system with Caco-2 cells and Anisakis exosomal microRNAs” and “Exploring pathogenicity and tumorigenic potential of Anisakis pegreffii using intestinal organoids” coordinated by Serena Cavallero and Prof. Stefano d’Amelio, Department of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy.
  • Collaboration with Federica Facciotti, Department of Experimental Oncology, European Institute of Oncology (IEO), Milan, Italy, within the research project entitled “Mucosa- associated E. coli drive pathogenic functions in IBD-derived intestinal NKT cells.”
  • Participation in the research activities of the project entitled: “Evaluation of the impact of bacterial superinfections in post-COVID-19 patients and surveillance on antimicrobial resistance of major pulmonary ” supervised by Dr. Cecilia Ambrosi. Department of Human Sciences and Promotion of the Quality of Life, San Raffaele Roma Open University, Rome, Italy
  • Member of the Research Group of the “Organoids” Laboratory, Department of Public Health and Infectious Diseases, Sapienza University of Rome, directed by Prof. Anna Teresa Palamara. Ongoing research projects are: “Developing of bacteria-organoids co-cultivation experimental models.” and “Developing of beneficial E. coli-based probiotics in IBD patient- derived intestinal organoids.”

REVIEWER AND EDITORIAL BOARDS

https://www.mdpi.com/journal/foods/submission_reviewers

AWARDS AND GRANTS

Funded Projects:

  • Starting Grant Project (Ricerca Finalizzata 2018) from the Italian Ministry of Health; 2020- € 130.000 (Role: coordinator and PI).
  • Consultancy award assigned by the company I.I.T., Innovative Healthcare Products for the classification approval of the product based on D-mannose as a medical device. 2019-2020. €5.000 (Role: project responsible and PI).
  • E-COST-GRANT-CA21108-6e0a82cc” through international collaboration hosted by Biocenter, Institute of Molecular Biology, Medical University of Innsbruck, 2023-07 to 2023-08.
  • Visiting Scientist through international collaboration at Microbiology Research Center (MRC), Pasteur Institute of Tehran, 1/12/2017–30/11/2018. Taring school. COST ACTION CA17140. Cancer Nanomedicine: from bench to bedside, Institute of Oncology Research (IOR), Bellinzona, Switzerland.
  • Doctoral Fellowship Grant from Sapienza University of Rome, FILAs Foundation Group; 2017-2018. € 000 (Role: coordinator and PI).
  • Scholarships from Sapienza University of Rome, LAZIODISU Foundation 2016-2019.
  • Best abstract award on “Comparison of the disk diffusion and polymerase chain reaction for the detection of antibiotic resistance Escherichia coli”. The NationalStudent’s Congress on Infections& Drug Resistance, May 1-2, 2013, Guilan, Iran.
  • Best abstract award on “Application of 16S and 23S rDNA target genes for the detection and screening of three common enteric bacterial pathogens using oligonucleotide macroarray”. The 4th student and researchfestival, BUMC, 2013, Tehran, Iran.
  • Best abstract award on “Frequency of clinical isolates of Salmonella enterica serotype in Tehran at 2009-2011”. The 3rd student and research festival, 2012, BUMC, Tehran,
  • Scientific award as creative and innovative young researcher at the 4th Iranian Superior young 2012, Tehran, Iran.
  • Best article award on “Use of 23S rDNA gene diversity for the discrimination of foodborne pathogenic bacteria by oligonucleotide microarrays”. The 4th Ditan International Conference on Infectious Diseases, 15-18 July 2010, Beijing,

TEACHING ACTIVITIES

Elective teaching activity for the course in Microbiology of the international sector of the Faculty of Medicine and Surgery at the Sapienza University of Rome relating to the academic’s years of 2017-2018 on Helicobacter pylori and 2018-2019, 2019-2020 on Enterobacteriaceae.

PATENTS

  1. Versatile blade holder surgical instruments, Registration number: 69770 [InPersian].
  2. Simultaneous diagnostic kit of water and foodborne pathogenic bacteria, Registration number:73685 [In Persian].
  3. Bacterial Nucleic acid(DNA) extraction kit, Registration number: 74971 [In Persian].
  4. Diagnostic kit of four bacterial species in the genus of enterica, Registration number: 77105 [InPersian].
  5. Molecular diagnostic kit of cholerae, Sh. dysenteriae and S. enterica. Registration number: 76034 [In Persian].

COURSES

  • Training course in theoretical and practical aspects of cell lines, human induced pluripotent and mesenchymal stem cells 20-24 August 2017, Transplant Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
  • Second International Course on Viruses and Human 01 – 09 July 2016. Institute Pasteur of Rome, Italy.
  • Bioinformatics: Theory and Applications from Genomes to June 5th – July 5th, 2017. School of Molecular Biology and Medicine. Sapienza University of Rome, Rome, Italy.
  • Practical Course on Molecular Phylogeny and Population 24 – 26 March 2015. Roma TRE University, Rome, Italy.

MEMBERSHIPS

  • Scientific Board, COST Action CA21145 (European Network for diagnosis and treatment of antibiotic-resistant bacterial infections). 2022-Present.
  • Scientific Board, COST Action CA20110 (RNA communication across kingdoms: new mechanisms and strategies in pathogen control). 2022-Present.
  • Italian Society of Microbiology. 2016 – Present. Microbiota Research Group of Iran. 2017 – Present.
  • Microbiology Research Center(MRC), Pasteur Institute of Iran. 2014 – Present. Iranian Young Researchers& Elite Club. 2012 – Present.
  • Iranian Inventors Association. 2011 – Present. Iranian Society of Microbiology. 2009 – Present.